Microplastics is found in human bones – and it weakens them
Microplastics is found in human bones – and it weakens them
Microplastics is found not only in oceans and on the beaches. These tiny particles are also found inside the human body, including the brain, sperm, light and blood vessels. Plastic enters the body through air, water and food. Tires, textiles, packaging and thrown objects - all this brings the smallest particles into the air, soil and water. Small particles can move with blood flow and settled in tissues.
New studies show how microplastics can affect the health of bones and bone marrow. Researchers from Brazil, Canada and France conducted a meta -analysis of 62 studies to explain the effects of microplasty on bone tissue. The work went outOsteoporosis International.
One of the leading authors, Rodrigo B. Oliveira from the State University of Campinas in Brazil: "For example, in vitro studies showed that microplastics worsens cell viability, accelerate their aging and cause inflammation."
over, the average level of microplasty deposition in the bones is dozens of particles per gram.
The study describes changes in cell behavior that are important for bone strength. The signals that contribute to the maturation of cells were weakened, while signals that contribute to the destruction of bones, on the contrary.
In some models, the balance is inclined in favor of osteoclasts - cells that remove the old bone. Too intense removal, called bone resorption, makes the skeleton more fragile over time.
Microplasty cells can distinguish inflammatory molecules, which confuses the process of bone renewal. This can lead to an increased level of chemical stress inside bone cells.
Researchers also report that microplastics can penetrate into deeper bones, including bone marrow. Disruption of the bone marrow apparatus can negatively affect both the formation of blood cells and on the renewal of bones.
Age and hormonal changes already lead to a loss of bone mass. Additional stress from microplasty can aggravate the problem, especially in people with other risk factors. The International Osteoporosis Foundation predicts that the number of fractures of the hip joint will almost double by 2050 compared to 2018.
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